⚕ AMR-Guard
Infection Lifecycle Orchestrator · Multi-Agent Clinical Decision Support
System Overview
WHO AWaRe
264
antibiotics classified
EUCAST
v16.0
breakpoint tables
IDSA
2024
treatment guidelines
DDInter
191K+
drug interactions
Agent Pipeline
Stage 1 — Empirical (no lab results yet)
Agent 01
Intake Historian
Parses patient data, calculates CrCl, identifies MDR risk factors
Agent 04
Clinical Pharmacologist
Empirical antibiotic selection · WHO AWaRe · safety screening
Stage 2 — Targeted (culture / sensitivity available)
Agent 01
Intake Historian
Same as Stage 1
Agent 02
Vision Specialist
Extracts structured data from lab reports (any language / format)
Agent 03
Trend Analyst
Detects MIC creep · calculates resistance velocity
Agent 04
Clinical Pharmacologist
Targeted recommendation informed by susceptibility data
AI Models (Local)
| Agent | Role | Model |
|---|---|---|
| 1, 2, 4 | Clinical reasoning | google/medgemma-4b-it |
| 3 | Trend analysis | google/medgemma-4b-it |
| 4 (safety) | Pharmacology check | google/txgemma-2b-predict |
| — | Semantic retrieval | sentence-transformers/all-MiniLM-L6-v2 |
| — | Inference backend | HuggingFace Transformers · 4bit quant |
⚠ Research demo only. Not validated for clinical use. All recommendations must be reviewed by a licensed clinician before any patient-care decision.
Patient Analysis Pipeline
Biological sex
Primary infection site
Suspected source
Urinary — Assessment
Catheter status
Urine appearance
Respiratory — Assessment
Ventilation status
Cough type
Sputum character
Bloodstream — Assessment
Shock status
Skin — Assessment
Wound type
Cellulitis extent
Intra-Abdominal — Assessment
Pain location
Cns — Assessment
Medical History
Lab / Culture Results (optional — triggers targeted pathway)
Results
Susceptibility Table
Clinical Tools
Select tool
Infection type
WHO AWaRe
● Access — first-line
● Watch — second-line
● Reserve — last resort
● Access — first-line
● Watch — second-line
● Reserve — last resort
Interpretation guide
S Susceptible — antibiotic is effective
I Intermediate — effective at higher doses
R Resistant — do not use
S Susceptible — antibiotic is effective
I Intermediate — effective at higher doses
R Resistant — do not use
2 6
Clinical Guidelines Search
Filter by pathogen
Sources: IDSA Treatment Guidelines 2024 · EUCAST Breakpoint Tables v16.0 · WHO EML · DDInter drug interaction database.